BDS · Periodontology · TOPIC 06 Periodontal Disease Why teeth become loose — biofilm, host response, and the bone that quietly disappears Periodontitis is the commonest reason adults lose teeth — more than caries, more than trauma. The disease is paradoxical: it is bacterially initiated (no plaque, no disease) yet the tissue destruction is overwhelmingly host- mediated — your own neutrophils, cytokines, and osteoclasts dismantle the periodontium in a misdirected attempt to wall off the biofilm. Understanding this twin engine — biofilm + host response — is the entire game. ▸ …
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